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Mephedrone is an amphetamine and cathinone class drug. An amphetamine is a drug with a stimulant effect on the (CNS) central nervous system that can be physically and psychologically addictive when used too much.Buy Mephedrone (4-MMC) Crystal Powder Online

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Buy Mephedrone (4-MMC) Crystal Powder Online

Mephedrone is an amphetamine and cathinone class drug.Buy Mephedrone (4-MMC) Crystal Powder Online An amphetamine is a drug with a stimulant effect on the (CNS) central nervous system that can be physically and psychologically addictive when used too much. Cathinone is a naturally occurring stimulant present in the Khat plant. Its structure and effects are similar to those of ephedrine and amphetamine.Mephedrone is a synthetic (artificial) substance based on the (cathinone) compounds that exist in the Khat plant of East Africa. Users may swallow, snort or inject mephedrone.Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include bath salts, drone,M-CAT,White Magic and meow meow.It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa.It comes in the form of tablets or a powder, which users can swallow, snort or inject, producing similar effects to MDMA, amphetamines and cocaine..The metabolism of mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage.Mephedrone was first synthesised in 1929, but did not become widely known until it was rediscovered in 2003 at which point it was legal to produce and possess in many countries. By 2007, mephedrone was reported to be available for sale on the internet, by 2008 law enforcement agencies had become aware of the compound, and by 2010, it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom. Mephedrone was first made illegal in Israel in 2008, followed by Sweden later that year. In 2010, it was made illegal in many European countries and in December 2010, the EU ruled it illegal. In Australia, New Zealand and the United States, it is considered an analog of other illegal drugs and can be controlled by laws similar to the US Federal Analog Act. In September 2011, the US temporarily classified mephedrone as a Schedule I drug, effective October 2011. This classification was made permanent in July 2012 with the passage of the Synthetic Drug Abuse Prevention Act (SDAPA).Users have reported that mephedrone causes euphoria, stimulation, an enhanced appreciation for music, an elevated mood, decreased hostility, improved mental function and mild sexual stimulation; these effects are similar to the effects of cocaine, amphetamines and MDMA, and last different amounts of time depending on the way the drug is taken. Of 70 Dutch users of mephedrone, 58 described it as an overall pleasant experience and 12 described it as an unpleasant experience.In a survey of UK users who had previously taken cocaine,Buy Mephedrone (4-MMC) Crystal Powder Online most users found it produced a better-quality and longer-lasting high and was less addictive. The users were also asked to compare the “risk”, and they answered that it was equal.A study of users in Northern Ireland found they did not equate the fact that mephedrone was legal with it being safe to use. This was contrary to another study in New Zealand, where users of benzylpiperazine thought that because it was legal, it was safe.Mephedrone can come in the form of capsules, tablets or white powder that users may swallow, snort, inject, smoke or use rectally.When taken orally, users reported they could feel the effects within 15–45 minutes; when snorted, the effects were felt within minutes and peaked within half an hour. The effects last for between two and three hours when taken orally or nasally, but only half an hour if taken intravenously.It is sometimes sold mixed with methylone in a product called bubbles in the UK and also mixed with other cathinones, including ethcathinone, butylone, fluoromethcathinone and methedrone.One published study that analysed samples of mephedrone bought using the internet in the UK in 2010 found it was racemic (a mixture of both stereoisomers) and of high purity.An unpublished study of six samples also ordered off the internet in the UK in 2010 found they contained very few organic impurities.Four products sold in Irish head shops were tested in 2010 and were found to contain between 82% and 14% mephedrone, with some products containing benzocaine and caffeine.The ECMDDA reported mephedrone can cause various unintended side effects including: dilated pupils,poor concentration, teeth grinding, problems focusing visually, poor short-term memory, hallucinations, delusions, and erratic behaviour.They noted the most severe effects appear anecdotally to be linked with high doses or prolonged use, and the effects may be due to users taking other intoxicants at the same time. Other effects users in internet forums have noted include changes in body temperature, increased heart rate, breathing difficulties, loss of appetite, increased sweating, discolouration of extremities, anxiety, paranoia and depression.When snorted, it can also cause nose bleeds and nose burns.A survey conducted by the National Addiction Centre, UK, found 67% of mephedrone users experienced sweating, 51% suffered from headaches, 43% from heart palpitations, 27% from nausea and 15% from cold or blue fingers,[18] indicative of vasoconstriction occurring.Doctors at Guy’s Hospital, London reported that, of 15 patients they treated after taking mephedrone in 2009, 53% were agitated, 40% had increased heart rates, 20% had systolic hypertension and 20% had seizures; three required treatment with benzodiazepines, predominantly to control their agitation. They reported none of their patients suffered from cold or blue peripheries,Buy Mephedrone (4-MMC) Crystal Powder Online contrary to other reports. Nine of the 15 of patients had a Glasgow coma scale (GCS) of 15, indicating they were in a normal mental state, four had a GCS below 8, but these patients all reported using a central nervous system depressant, most commonly GHB, with mephedrone. The patients also reported polydrug use of a variety of compounds.Neurotoxic effect of mephedrone on serotonin (5-HT) and dopamine (DA) systemsBuy Mephedrone (4-MMC) Crystal Powder Online remains controversial. Although some studies in animal models reported no damage to DA nerve endings in the striatum and no significant changes in brain monoamine levels, some others suggested a rapid reduction in 5-HT and DA transporter function. Persistent serotonergic deficits were observed after binge like treatment in a warm environment and in both serotonergic and dopaminergic nerve endings at high ambient temperature. Oxidative stress cytotoxicity and an increase in frontal cortex lipid peroxidation were also reported.Mephedrone is a monoamine releasing agent. It is a chiral compound and both of its enantiomers display similar potency as substrates at dopamine transporters. R-Mephedrone is much less potent than S-mephedrone as a substrate at serotonin transporters.The keto oxygen renders mephedrone more hydrophilic than the corresponding methylamphetamines, which may account for the higher doses required to achieve a similar effect, because mephedrone is less able to cross the blood–brain barrier.Mephedrone is often consumed with alcohol. A study in mice investigated the interrelation between these two substances, focusing on the psychostimulant and rewarding properties of mephedrone.Buy Mephedrone (4-MMC) Crystal Powder Online It found that at low (non stimulant) doses alcohol significantly enhanced the psychostimulant effects of mephedrone. This effect was mediated by an increase in synaptic dopamine, as haloperidol, but not ketanserin, was able to block the potentiation by alcohol. Similarly, the rewarding properties of mephedrone were enhanced by a low non-rewarding dose of alcohol.Buy Mephedrone (4-MMC) Crystal Powder Online,Order Mephedrone (4-MMC) Crystal Powder Online,Purchase Mephedrone (4-MMC) Crystal Powder Online

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